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Data report · Recomputed monthly · August 2026

$50,000+ Business Grants Open Now — August 2026

68 US business grant programs advertising a maximum award of $50,000 or more were open on August 24, 2026 — 38 state, 20 federal, 6 city or county, and 4 private or foundation. The tier's real price is not the odds. A $50,000-plus application in the GrantCompass catalog takes a median of 24.5 hours to prepare, against 4 hours for open grants under $25,000, while mean competitiveness barely moves (3.28 versus 2.90 on a 1–5 scale). 30 of the 68 pay by match or reimbursement, so the business funds the work before the grant funds the business. Nine rows arrived carrying a status note that had to be checked against the funder’s own page; six of the nine turned out to be stale in our catalog and are corrected here, three still stand, and today’s checks raised one new flag. Four rows say Check status.

68grants of $50K+ open today
$250Kmedian advertised ceiling
24.5 hmedian application, this tier
30pay by match or reimbursement

Updated August 24, 2026 — every amount, deadline and status featured in prose below was re-read at the administering agency's own page on August 24, 2026. Table rows carry the GrantCompass catalog's stored values. Recomputed monthly; permanent URL.

See every program you qualify for — free →A two-minute eligibility check ranks all 665 US programs against your business. No card, no pitch deck.

Every $50,000+ grant that is open, with what it costs you

All 68 open programs, largest advertised ceiling first. Filter by intake type, state, industry and award floor. The fourth column is the one most lists omit: whether the money arrives as a direct payment, only against a matching contribution, or as a reimbursement of costs you have already paid. Rows marked Check status are the four whose intake could not be confirmed as live on August 24, 2026. Rows whose note opens with a tick were re-read at the administering agency’s own page that day, and where the agency disagreed with our stored record the agency’s version is what you see.

Showing 68 of 68 programs of $50,000 or more

ProgramAdvertised ceilingIntakeHow the money arrivesLevelWin Layer
ARPA-H Innovative Solution Openings (ISOs) — Health Technology OT Agreements
Rolling — ARPA-H publishes ISOs continuously. Check arpa-h.gov/explore-funding/open-funding-opportunities for current …
Varies — typically $1M–$50MRollingPaid directFederal · All US6 locked
DOE Office of Energy Efficiency and Renewable Energy (EERE) Funding Opportunity Announcem…
Rolling — multiple FOAs open at any given time. Search eere.energy.gov/funding or grants.gov for current active opport…
$500K–$20M+ per awardRollingMatch / cost-shareFederal · All US6 locked
North Carolina Film and Entertainment Grant
Rolling — apply to NC Film Office before production. Annual fund has a July 1–June 30 fiscal year window.
25% of qualifying NC spendRollingReimbursedState · NC6 locked
DOE Advanced Nuclear Energy Licensing Cost-Share Grant Program
September 30, 2026
Varies (cost-share structure)Sep 30, 2026
37 days
Match / cost-shareReimbursedFederal · All US6 locked
EDA Public Works & Economic Adjustment Assistance (PWEDA)
Rolling applications accepted year-round. No fixed annual deadline — submit when project is ready. Applications review…
$100K–$10,000,000+RollingPaid directFederal · All US6 locked
OSD ManTech Advanced Manufacturing Technology Program
Rolling — opportunities posted on Grants.gov as they arise under CFDA 12.333. No fixed annual cycle. Subscribe to Gran…
$150,000–$8,800,000RollingPaid directFederal · All US6 locked
Wyoming Business Ready Community Grant & Loan Program
✓ Cities, towns, counties and joint-powers boards are the primary applicants; a business takes part as the committed employer (Wyoming Business Council, verified Aug 23 2026).
Up to $5,000,000RollingPaid directState · WY6 locked
DOE Office of Science — FY2026 Continuation of Solicitation for the Financial Assistance…
September 30, 2026
$50K–$5,000,000/yearSep 30, 2026
37 days
Match / cost-shareFederal · All US6 locked
One North Carolina Fund
Rolling — no annual cycle. Applications submitted through NC Commerce Business Services Division as projects are in ac…
Varies — typically $100K–$5MRollingPaid directState · NC6 locked
Tennessee FastTrack Economic Development Fund
✓ Negotiated through a local government during active site selection; there is no public application portal (TNECD, verified Aug 23 2026).
Negotiated; $250K–$5M typicalRollingPaid directState · TN6 locked
Minnesota Job Creation Fund
✓ Deal-by-deal through Minnesota DEED. DEED's published ceiling is up to $1,000,000, well below the stored range (checked Aug 23 2026).
Varies — typically $500K–$3MRollingPaid directState · MN6 locked
LPS Qubit Collaboratory (LQC)
Rolling — BAA open through April 30, 2027; proposals accepted on a continuous basis
Up to $800K/yrApr 30, 2027Match / cost-shareFederal · All US0 locked
SBIR Phase II — NIH (PHS Omnibus)
✓ September 5, 2026 is a standard PHS omnibus receipt date (Cycle I; January 5 and April 5 follow) — NIH due-date schedule, checked Aug 24 2026. The stored 'between intakes' label understates this.
Up to $2.15M (Phase II)Sep 5, 2026
12 days
Paid directFederal · All US7 locked
STTR Phase II — NIH (PHS Omnibus)
✓ September 5, 2026 is a standard PHS omnibus receipt date (Cycle I; January 5 and April 5 follow) — NIH due-date schedule, checked Aug 24 2026. The stored 'between intakes' label understates this.
Up to $2.15M (STTR Phase II)Sep 5, 2026
12 days
Paid directFederal · All US7 locked
SBIR Phase II — Department of Defense
Component-dependent — DoD Phase II applications are submitted by invitation from the component that funded Phase I, ty…
Up to $2M (Phase II)RollingPaid directFederal · All US7 locked
NOAA Fisheries Broad Agency Announcement (BAA) FY 2024–2026
Rolling — BAA open through September 30, 2026 (11:59 PM EDT)
Up to $1.6M est. totalSep 30, 2026
37 days
Paid directFederal · All US0 locked
EDA Economic Adjustment Assistance — Revolving Loan Fund (RLF) Program
Rolling — EDA accepts RLF applications under its standing FY2025 Public Works and Economic Adjustment Assistance NOFO.…
$800K–$1.4M (to RLF operator)RollingPaid directFederal · All US6 locked
SBIR Phase II — NSF (America's Seed Fund)
Phase II applications are submitted by invitation after Phase I completion. NSF invites Phase I awardees to submit Pha…
Up to $1M (Phase II)RollingPaid directFederal · All US7 locked
NYSERDA FlexTech — Flexible Technical Assistance Program (Energy Studies)
✓ NYSERDA's FlexTech page is script-rendered and could not be machine-read on August 24, 2026; the stored cost-share share and ceiling are unconfirmed at source.
50-75% cost-share, up to $1MRollingMatch / cost-shareState · NY6 locked
CDC/NIOSH Commercial Fishing Occupational Safety Research Cooperative Agreement
✓ Next standard receipt date August 28, 2026 — corrected from August 25 on Aug 23, 2026 against the notice of funding opportunity's due-date schedule.
$150K–$975KAug 28, 2026
4 days
Match / cost-shareFederal · All US6 locked
Arizona Job Training Program
Rolling — applications accepted through the Arizona Commerce Authority subject to annual funding availability.
Up to 75% of training costsRollingReimbursedState · AZ6 locked
Texas Skills Development Fund
✓ Year-round. The applicant of record is a Texas public community or technical college, TEEX or TEES — not the business (Texas Workforce Commission, checked Aug 24 2026).
Up to $500,000RollingPaid directState · TX6 locked
Ben Franklin Technology Partners — Seed Investment Program
Rolling — Healthcare applications reviewed continuously. Technology applications on scheduled review cycles. Contact y…
$50,000–$500,000RollingPaid directState · PA6 locked
Idaho Workforce Development Council — Employer Training Grant
✓ Quarterly review. The next published cutoff is September 4, 2026 at 5pm for the October committee — not the stored June 22 date (Idaho Workforce Development Council, verified Aug 23 2026).
Up to $500,000CyclicalReimbursedState · ID6 locked
Oregon Business Expansion Program (Business Oregon Expansion Fund)
Rolling — Business Oregon accepts applications year-round, subject to available annual budget. Engage regional project…
Negotiated; income-tax-basedRollingPaid directState · OR6 locked
Maryland Innovation Initiative (MII)
Quarterly submissions due by 5:00 PM on January 15, April 15, July 15, and October 15 each year.
Up to $480K in two phases (joint)CyclicalPaid directState · MD6 locked
City of Dallas Small Business Assistance Program (SBAP)
Rolling — no fixed application window. Applications reviewed as submitted. Project must not have begun before applicat…
Up to $400,000RollingPaid directLocal · TX6 locked
SBIR Phase I — NIH (PHS Omnibus)
✓ September 5, 2026 is a standard PHS omnibus receipt date (Cycle I; January 5 and April 5 follow) — NIH due-date schedule, checked Aug 24 2026. The stored 'between intakes' label understates this.
Up to $323,090Sep 5, 2026
12 days
Paid directFederal · All US1 locked
STTR Phase I — NIH (PHS Omnibus)
✓ September 5, 2026 is a standard PHS omnibus receipt date (Cycle I; January 5 and April 5 follow) — NIH due-date schedule, checked Aug 24 2026. The stored 'between intakes' label understates this.
Up to $323,090 (STTR Phase I)Sep 5, 2026
12 days
Paid directFederal · All US7 locked
SBIR Phase I — NSF (America's Seed Fund)
Between intakes — Project Pitch submissions paused as of April 16, 2026; NSF expects to resume in coming weeks. Prior …
Up to $305K (Phase I)Nov 4, 2026 Check statusMatch / cost-shareFederal · All US1 locked
STTR Phase I — NSF
Rolling Project Pitches (paused as of May 2026 — expected to resume in coming weeks per NSF). Full proposals submitted…
Up to $305,000Check status Check statusPaid directFederal · All US1 locked
DOE ITAC Implementation Grant — Small Manufacturer Energy Efficiency
✓ Active — up to $300,000 per qualified assessment recommendation, applied for through the EnergyWerx portal (US DOE MESC, checked Aug 24 2026). The stored 'on hold' note is stale.
Up to $300,000RollingMatch / cost-shareFederal · All US6 locked
Draper Richards Kaplan Foundation — Impact Funding
Rolling — applications accepted year-round, no fixed deadline
Up to $300K over 3 yrsRollingPaid directFoundation · All US6 locked
STTR Phase I — Department of Energy
Annual solicitation — DOE STTR Phase I is released as an annual FOA (Funding Opportunity Announcement). FY2026 Phase I…
$200K–$250K (STTR Phase I)Sep 10, 2026
17 days
Paid directFederal · All US7 locked
Alabama Innovation Grant (SBIR/STTR State Match)
Periodic rounds — check innovatealabama.org for open application windows. Not rolling.
Up to $250,000Check status Check statusPaid directState · AL6 locked
Chicago INVEST South/West Small Business Grant
Rolling — DPD opens application windows by corridor; check invest-sw.chicago.gov for current open corridors
Up to $250,000RollingPaid directLocal · IL6 locked
Colorado Advanced Industries Accelerator (AIA) Grant Program
✓ Open — the Advanced Industries Early-Stage Capital & Retention and Proof of Concept sub-grants both close August 27, 2026 at 5pm MT (OEDIT, checked Aug 24 2026). The stored 'FY2026 dates TBA' text is stale.
Up to $150K or $250KAug 27, 2026
3 days
Paid directState · CO6 locked
Utah Rural Employment Development Incentive (REDI) Grant
✓ Quarterly windows: February 1–15, May 1–15, August 1–15, November 1–15. $6,000 per new rural job against a $250,000 annual programme cap (Utah GOEO, checked Aug 24 2026).
Up to $6,000/jobCyclicalPaid directState · UT6 locked
Chicago Neighborhood Opportunity Fund (NOF)
Rolling intake with quarterly review cycles. Recent published deadlines include mid-May (Q2), mid-August (Q3), and mid…
Up to $250,000RollingReimbursedLocal · IL6 locked
Wyoming SBIR/STTR Match Grant
✓ Year-round; applicants are notified within about two weeks of the virtual pitch (Wyoming Business Council, checked Aug 24 2026).
Up to $100K (Ph I) / $200K (Ph II)RollingPaid directState · WY6 locked
Minnesota Job Skills Partnership (MJSP)
Rolling — DEED accepts applications year-round and reviews on a rolling basis. No fixed cycles.
Up to 50% of training costsRollingMatch / cost-shareState · MN6 locked
Minnesota Job Training Incentive Program (JTIP)
Rolling — applications accepted year-round on a first-come, first-served basis until funds are exhausted.
$5,000–$9,000 per new jobRollingReimbursedState · MN6 locked
Delaware EDGE Grant (Encouraging Development, Growth & Expansion) — EDGE 2.0
✓ Accepting applications through September 11, 2026. Awards are scaled from a $750,000 STEM pool and a $400,000 Entrepreneur pool across up to 18 winners (Delaware Division of Small Business, checked Aug 24 2026).
Up to ~$175,000 (scaled; no fixed cap)Sep 11, 2026
18 days
Match / cost-shareState · DE6 locked
Chicago Small Business Improvement Fund (SBIF)
Rolling — monthly application windows by TIF district; see rollout calendar at chicago.gov/sbif
Up to $150,000RollingMatch / cost-shareReimbursedLocal · IL6 locked
Colorado Existing Industry Customized Training Program
Rolling — applications accepted through OEDIT subject to annual appropriations.
Up to $1,500/employee; $150K maxRollingReimbursedState · CO6 locked
Connecticut Innovations Pre-Seed Investment Program
Rolling — pitch decks accepted year-round. Initial response within one week.
Up to $150K pre-seedRollingPaid directState · CT6 locked
Nebraska Innovation Fund Prototype Grant
Rolling — accepted on a rolling basis until funds are exhausted; FY26–27 applications open on or before July 1, 2026.
Up to $150,000RollingMatch / cost-shareState · NE6 locked
Connecticut Manufacturing Innovation Fund Voucher Program (MVP)
✓ Rolling and first-come; the $100,000 ceiling is confirmed at CCAT (checked Aug 24 2026). The match ratio and the Connecticut-tenure rule are not on a machine-readable official page — confirm with CCAT first.
$6,250–$100,000RollingMatch / cost-shareState · CT6 locked
Maryland Industrial Partnerships (MIPS) Program
Quarterly proposal deadlines. Notifications issued within 60 days of each deadline.
Up to $100,000/yearCyclicalPaid directState · MD6 locked
Connecticut Innovations Proof-of-Concept Fund
Rolling — pitch decks/business plans accepted year-round. Initial response within one week. Full due diligence 3.5–24 …
$50K–$100K convertible noteRollingPaid directState · CT6 locked
WEDnetPA — Pennsylvania Workforce and Economic Development Network
✓ Per-worker cap $2,000; per-company annual cap is $50,000, not the $100,000 stored here. The FY2026-27 cycle opened August 1, 2026 (WEDnetPA, checked Aug 24 2026).
Up to $2,000/worker; $100K maxRollingReimbursedState · PA6 locked
Detroit Motor City Match
Quarterly cohort — four rounds per year. Check motorcitymatch.com for current cycle open date.
Up to $100,000CyclicalMatch / cost-shareLocal · MI7 locked
IFundWomen Universal Grant Application
Rolling — submit the Universal Application any time to enter the matching database. Individual grant cycles have speci…
$10,000–$25,000 (varies by sponsor)RollingPaid directPrivate · All US6 locked
Missouri Technology Corporation (MTC) Proof of Concept Grant
Quarterly application cycles — specific deadlines published on MTC website. Applications reviewed by independent commi…
Up to $100,000CyclicalPaid directState · MO6 locked
WorkInvestNH (New Hampshire Job Training Fund)
Rolling — applications accepted year-round, but must be submitted at least 60 days before the planned training start d…
$750–$100,000 (50% match)RollingMatch / cost-shareReimbursedState · NH6 locked
Indiana FAST Program — SBIR/STTR Matching Grant
Rolling — applications processed after federal SBIR/STTR Phase II award is received.
Up to $75,000 per Phase II awardRollingPaid directState · IN6 locked
Wyoming Workforce Development Training Fund — Business Training Grants
Rolling — applications accepted year-round. Must be submitted 30–110 days before training begins.
Up to $4,000/trainee/yearRollingReimbursedState · WY6 locked
Illinois Innovation Voucher Program
Rolling within each round until funds are exhausted. Round 3 application window opened February 2, 2026.
Up to $75,000RollingMatch / cost-shareState · IL6 locked
Arizona Advanced Manufacturing Facilities (AMF) Grant
✓ Not listed under this name on the Arizona Commerce Authority's current programme index (checked Aug 24 2026). Confirm it exists before scoping a project around it.
Up to $75,000 (1:1 match)Check status Check statusMatch / cost-shareState · AZ6 locked
Elevate Vermont — SBIR/STTR Matching Grant
✓ Non-competitive and first-come, year-round, for companies that already hold a federal SBIR or STTR award. Five awards per business, lifetime (Vermont ACCD, checked Aug 24 2026).
Up to $50,000RollingPaid directState · VT6 locked
Maine Technology Institute (MTI) Business Innovation Seed Grant
Rolling — no fixed deadline. Apply when your project is ready. MTI evaluates applications continuously.
$5,000–$50,000RollingMatch / cost-shareState · ME6 locked
SCRA Technology Startup and Acceleration Grants
Rolling — applications are invited by assigned SCRA investment manager after achieving SCRA Member Company status
$25K–$50K non-dilutiveRollingMatch / cost-shareState · SC6 locked
Amber Grant for Women
Rolling — monthly, last day of each calendar month
$10K/mo + $50K year-endRollingPaid directPrivate · All US0 locked
Indiana Skills Enhancement Fund (SEF)
Rolling — applications accepted throughout the year subject to biennium funding availability.
Up to $50,000/bienniumRollingReimbursedState · IN6 locked
Philadelphia COVID-19 Small Business Relief Grant / Commerce Department Small Business Gr…
Rolling — multiple programs open periodically; check business.phila.gov for current open intake windows
Up to $50,000RollingPaid directLocal · PA6 locked
NC IDEA SEED Grant
✓ Fall 2026 cycle closes August 24, 2026 at 5:00pm ET, no exceptions (NC IDEA, checked Aug 24 2026).
$50,000Aug 24, 2026
today
Paid directPrivate · NC7 locked
VIPC Launch Program (Commonwealth Commercialization Fund)
✓ Quarterly solicitations, roughly 20 selections a year (VIPC, verified Aug 23 2026). The stored 'rolling' cadence was wrong.
$50,000RollingMatch / cost-shareState · VA6 locked
Connecticut Manufacturing Innovation Fund — Incumbent Worker Training (IWT) Program
Rolling — applications accepted on an ongoing basis through the CCAT grants portal while MIF funds remain
$2,500–$50,000/yr (50% match)RollingMatch / cost-shareReimbursedState · CT6 locked

68 rows is the market. Your list is much shorter. The free eligibility check runs your state, stage, industry and ownership against all 665 US programs and ranks what you genuinely qualify for — and you get free deadline alerts on anything you star.

See your matches — free →

Which $50,000+ business grants are open right now?

Short answer

Sixty-eight grant programs advertising $50,000 or more were accepting applications on August 24, 2026. State economic-development agencies run 38 of the 68, federal agencies 20, cities and counties 6, and private funders or foundations 4. Forty-five accept applications on a rolling basis, 13 carry a published deadline or federal receipt date still ahead, 6 run a cyclical window whose next date is unpublished, and 4 could not be confirmed as live and are marked accordingly. The median advertised ceiling across the 68 is $250,000, but the advertised ceiling is the wrong number to plan around: the GrantCompass catalog's realistic-payout note for these same programs typically lands at a fraction of the headline. Connecticut's Manufacturing Innovation Fund Voucher Program advertises up to $100,000 and its typical award sits in the $25,000–$75,000 band. The single most useful filter at this tier is not the amount — it is whether the money is paid direct or against a match.

Dated windows inside the next 60 days

Twelve of the 68 programs publish a specific date between August 24 and October 23, 2026. Four of the twelve are National Institutes of Health SBIR and STTR standard receipt dates of September 5, 2026, which recur three times a year rather than closing a window, and one — the DOE Office of Science FY2026 continuation solicitation — is a standing solicitation whose September 30 date does not shut a door. The seven genuine one-off closings are below, soonest first.

closes today

NC IDEA SEED Grant

$50,000 · closes Aug 24, 2026, 5:00pm ET · Private (NC)

3 days

Colorado Advanced Industries Accelerator

Up to $150K (Proof of Concept) / $250K–$500K (Early-Stage Capital) · closes Aug 27, 2026, 5pm MT · State (CO)

4 days

CDC/NIOSH Commercial Fishing Safety Research

$150,000–$975,000 · receipt date Aug 28, 2026 · Federal

17 days

STTR Phase I — Department of Energy

$200,000–$250,000 · Sep 10, 2026 · Federal

18 days

Delaware EDGE Grant

Scaled from a $750K STEM / $400K Entrepreneur pool · Sep 11, 2026 · State (DE)

37 days

DOE Advanced Nuclear Licensing Cost-Share

Cost-share, varies · Sep 30, 2026 · Federal

37 days

NOAA Fisheries Broad Agency Announcement

Up to $1.6M · BAA closes Sep 30, 2026 · Federal

How this section is built. Days remaining are measured from August 24, 2026. A program appears here only when the catalog stores a specific calendar date that has not passed and the date is inside 60 days. Recurring federal receipt dates are separated from one-off closings because they behave differently: missing September 5 at the National Institutes of Health costs four months, not the cycle. The DOE Office of Science FY2026 continuation solicitation also carries September 30, 2026 and is excluded from these cards because it is a standing solicitation rather than a single window. The Colorado card exists because our stored record said “FY2026 dates TBA” while the Colorado Office of Economic Development and International Trade’s own pages, read on August 24, 2026, show both Advanced Industries sub-grants open with a hard August 27 close. Every dollar figure on these seven cards was read at the administering agency’s page that day, except the Delaware pool figures, which come from the Delaware Division of Small Business EDGE page and its FAQ.

What a $50,000 grant demands that a $10,000 grant does not

Original finding

Moving from the under-$25,000 tier to the $50,000-and-up tier multiplies the application by roughly six and leaves the odds almost unchanged. Across the open grant programs in this dataset, the median estimated application at $50,000 or more takes 24.5 hours; the median under $25,000 takes 4 hours. Mean competitiveness moves from 2.90 to 3.28 on a 1–5 scale — a 13% increase for a six-fold increase in work. Median accessibility, our 1–10 measure of how approachable the paperwork is, falls from 8 to 6. The premium at this tier is paid in hours and in documentation, not in a materially worse chance of winning.

Open grants under $25,000

Programs
29
Median hours
4
Mean competitiveness
2.90 / 5
Median accessibility
8 / 10

Open grants $25,000–$49,999

Programs
11
Median hours
12
Mean competitiveness
2.45 / 5
Median accessibility
7 / 10

Open grants $50,000 and up

Programs
68
Median hours
24.5
Mean competitiveness
3.28 / 5
Median accessibility
6 / 10

The extra hours buy three specific documents. Reading the intake descriptions across the 68, the work that separates a $50,000-plus application from a microgrant application is a project budget that ties every line to an eligible cost category, a narrative that quantifies an outcome the agency can report upward — jobs created, energy saved, a technology de-risked — and third-party attestation, which at this tier means an accountant, an engineer, a partnering college or a federal award letter you already hold. The Illinois Innovation Voucher Program, at up to $75,000, will not read a proposal that does not name the Illinois research institution doing the work. The Indiana FAST Program processes nothing until a federal Phase II award exists.

Time is also the reason the $50,000 tier is not automatically the better bet. Whether a longer application is worth it depends on the ratio of award to hours, which is the question our companion analysis of the fastest business grant applications takes apart directly. This page answers the narrower one: what changes about the work itself when the number gets larger.

Cost-share and matching at the $50,000+ tier

Quick answer

Thirty of the 68 open $50,000-plus programs — 44% — publish a matching, cost-share or reimbursement requirement in their own text. Twenty-one require a match or cost-share, meaning the business must commit its own money alongside the award. Thirteen are structured as reimbursements, meaning the business pays first and is repaid after the spend is documented. Four do both. At the microgrant tier this structure is rare; at $50,000 and above it is the norm, and it is the single largest reason a business that "wins" a grant at this tier still cannot use it.

A match is a cash-flow event, not a discount. On a 50% cost-share, a $60,000 award describes a $120,000 project: the agency pays half after you commit the other half, so the number in the headline is twice the number in your budget. New Hampshire's WorkInvestNH publishes its range as $750 to $100,000 at a 50% match; Connecticut's Manufacturing Innovation Fund Incumbent Worker Training programme publishes $2,500 to $50,000 a year, also at 50%; the Illinois Innovation Voucher Program, confirmed at the Illinois Department of Commerce and Economic Opportunity on August 23, 2026, covers up to 75% of the cost of research work done with an Illinois research institution. In every one of those cases the advertised ceiling describes the size of a project, not the size of a cheque.

Reimbursement is a different problem with the same symptom. Arizona's Job Training Program, Colorado's Existing Industry Customized Training Program and Chicago's Small Business Improvement Fund all pay against documented, already-incurred cost, and Chicago's cost-share ratio itself varies between 30% and 90% depending on the tax-increment district's budget. A business with $8,000 of monthly headroom cannot run a $120,000 reimbursed project regardless of how well it writes. The honest sequence at this tier is to establish how the money lands before writing a word, then size the project to the cash you can actually float. Our guide to how to apply for a small business grant covers the paperwork order; this page covers only what the $50,000-plus tier specifically adds.

How the 35 were counted. Each of the 68 programs' published title, advertised-amount string, deadline text, insider note and realistic-payout note was scanned for the terms match, cost share, cost-share, 1:1, 2:1, 3:1, 50/50, in-kind, reimburse and rebate. This is a text scan over published fields, not a curated flag, so it under-counts by construction: a match requirement that lives only in a programme's guidelines is invisible to it. The verification pass found exactly that: the South Dakota Proof of Concept Program carries a minimum 10% match that appears nowhere in its published amount string. It also over-counts in one specific way, corrected by hand here — a state SBIR or STTR “matching grant” is called that because the state matches your federal award, not because you must put up money, and IFundWomen's “matching database” is a database, not a cost-share. Five such rows were re-read and reclassified, taking the count from 35 to 30. Treat 30 of 68 as a floor. Per-programme ratios also move with fiscal-year rules, so confirm the current ratio with the administering agency before scoping. n=68, August 24, 2026.

Seven of the largest numbers on this page are not yours to apply for

Read this before the table

At the $50,000-plus tier a recurring pattern appears that does not exist in microgrants: the programme is real, the money is real, and the applicant of record is somebody else. A city applies. A community college applies. An economic-development officer negotiates a package during a site-selection process that a small business is never invited into. At least seven of the 68 programs here work that way, and they include several of the biggest advertised numbers on the page.

Wyoming's Business Ready Community Grant advertises up to $5,000,000 and is applied for by a municipality. The Wyoming Business Council's own programme page states that cities, towns, counties and joint-powers boards are the primary applicants; a business benefits as the committed tenant or employer, not as the grantee. The Texas Skills Development Fund advertises up to $500,000 and is applied for by a public community or technical college, the Texas A&M Engineering Extension Service or the Texas Engineering Experiment Station, which then delivers the training; the Texas Workforce Commission accepts proposals year-round, but not from you directly. Tennessee's FastTrack Economic Development Fund is negotiated through a local government during active site selection and has no public application portal at all.

The pattern continues down the list. The One North Carolina Fund and the Minnesota Job Creation Fund are deal-by-deal instruments evaluated by state business-development staff while a project is choosing between states; the Oregon Business Expansion Program is negotiated with Business Oregon regional project managers on a formula tied to the income tax generated by new jobs; the EDA Economic Adjustment Assistance Revolving Loan Fund awards $800,000 to $1,400,000 to the organisation that will operate a loan fund, not to the businesses that later borrow from it. Naming this pattern is not a criticism of the programmes — they are doing what they were designed to do. It is a criticism of every list that prints "up to $5 million" next to a small business's name.

What this means in practice. If your business is genuinely the applicant, the reachable end of this page is the state innovation, voucher, commercialization and training programmes in the $50,000 to $250,000 band, plus the federal research vehicles if you are retiring a technical risk. If a project of yours is large enough to move a county's employment numbers, the productive first call is not a grant portal — it is the regional economic-development officer, because the instrument that fits you is one they file.

Where $50,000+ grant money actually sits: state, not federal

State agencies run 38 of the 68 open programs at this tier, nearly double the 20 federal ones. That inverts where most founders look first, and it holds even though federal programmes carry far larger ceilings.

38State. Innovation vouchers, SBIR match, commercialization funds, customized-training money, job-creation rebates. 26 states appear.
20Federal. Mostly research vehicles — SBIR and STTR at NIH, NSF, DoD and DOE, plus EDA, NOAA, ARPA-H and DOE mission offices.
6City and county. Chicago, Detroit, Dallas and Philadelphia storefront, corridor and improvement funds — the most place-specific money on the page.
4Private and foundation. NC IDEA SEED, the Amber Grant's year-end awards, IFundWomen's sponsor-matched grants, and the Draper Richards Kaplan Foundation.

The state layer is also where the caveats concentrate differently from the federal layer. Federal caveats here are cyclical — the National Institutes of Health is between receipt dates, the National Science Foundation paused Project Pitch submissions in April 2026 — and they resolve on a published calendar. State caveats are budgetary: a rolling programme stays "open" in every listing until the appropriation is spent, and nothing announces the moment it runs out. That asymmetry is why this page prints the funder's own words in every row rather than a green dot. For the full state-by-state picture at every award size, see state small business grants open now; for the federal layer including what is not a grant at all, see federal small business grants open now.

The numbers behind the $50,000+ tier

68 open programs, a $250,000 median advertised ceiling, a 24.5-hour median application, and a 3.28 mean competitiveness score. Every figure on this page is computed from the same snapshot; the method is stated at the bottom of this section.

The 68 open $50,000+ grants, by level of government

  • Federal 20
  • State 38
  • City / county 6
  • Private / foundation 4

How the 68 intakes actually work

Rolling — apply any day
45 programs
Dated deadline or receipt date ahead
13 programs
Cyclical, next date unpublished
6 programs
Could not be confirmed as live
4 programs
Methodology. Population: the GrantCompass US catalog of 665 verified funding programs. Selection: fundingType = grant, programStatus = active, no passed deadline date, and amountMax ≥ $50,000 — 68 programs on August 24, 2026. The tier comparison uses the same open-grant test applied to the pilot extract's 125 open grant programs, split at $25,000 and $50,000 of advertised maximum (n=29 under $25,000, n=11 in the $25,000–$49,999 band, n=68 at $50,000 and above); it compares open grants within one dataset on one date, not the whole US grant market, and the sub-$25,000 group is the smaller sample. Hours are the catalog's estimated preparation hours for a competitive application (present for all 68). Competitiveness is a 1–5 editorial score, present for 67 of 68; accessibility is a 1–10 score of how approachable the paperwork is. Median advertised ceiling uses amountMax, present for all 68. Match and reimbursement counts come from the text scan described in the cost-share section. Amounts, deadlines and statuses featured in prose, in the dated cards and in the verdict below were re-read at the administering agency's own page on August 24, 2026; table rows print the catalog's stored values, and where the two disagreed the discrepancy is logged in the changelog rather than silently patched.

Which three of the 68 are actually worth your time

One person's read

I read all 68 rows to build this page. Most of them are excellent programmes for a business that is not yours — wrong state, wrong industry, wrong applicant. Three stand out as genuinely reachable at this tier by an ordinary operating company, and each is picked on the published numbers, not on brand. Each also has a gate, stated plainly.

1. Connecticut Manufacturing Innovation Fund Voucher Program (MVP)

$6,250–$100,000 · 8 hours · competitiveness 3/5 · accessibility 7/10 · rolling

Eight estimated hours against a $100,000 ceiling is the best work-to-ceiling ratio in the tier, and the intake is rolling and first-come rather than a once-a-year scramble. The Connecticut Department of Economic and Community Development runs it with the Connecticut Center for Advanced Technology; the $100,000 ceiling and the first-come structure were confirmed at CCAT on August 24, 2026, and typical awards land in the $25,000–$75,000 band rather than at the cap. The gate, stated honestly: this is a matching voucher, and the ratio matters enormously to whether it is worth eight hours — but the ratio and the Connecticut-tenure requirement are published only inside a portal that no machine-readable official page mirrors, and secondary sources disagree with each other. Call CCAT and ask two questions before you start: what is my match ratio as a first-time applicant, and how long must I have been registered in Connecticut. Worth your time if you are a Connecticut manufacturer with a defined equipment or process project and the cash to fund the larger share of it.

2. Wyoming SBIR/STTR Match Grant

Up to $100,000 Phase I / $200,000 Phase II · 10 hours · competitiveness 3/5 · accessibility 7/10 · rolling

Ten hours, applications open year-round, and a decision within roughly two weeks of a virtual pitch — the fastest decision cycle at this size anywhere in the 68. State SBIR match programmes are structurally the most winnable large grants in the United States because the hard selection already happened at the federal agency; the state is topping up a company it did not have to evaluate. The gate: you must already hold a federal SBIR or STTR award, and you must be a Wyoming company. If you hold a Phase I award and you are in one of the nineteen match states, apply in your own state before you look at anything else on this page.

3. Texas Skills Development Fund

Up to $500,000 · 25 hours · competitiveness 2/5 · accessibility 5/10 · rolling · typical project $50,000–$300,000

The largest number in the tier that an ordinary Texas employer can genuinely reach, and at competitiveness 2 of 5 it is among the least contested. The Texas Workforce Commission accepts proposals throughout the year. The gate is the biggest on this list and it is worth understanding rather than avoiding: the applicant is a public community or technical college, the Texas A&M Engineering Extension Service or the Texas Engineering Experiment Station, partnering with you; the money is paid to that institution, which delivers the training; you never see cash. If what you actually need is your workforce upskilled, that is a feature. If what you need is capital, this is the wrong programme and the state innovation and commercialization funds above are the right ones.

Honourable mention, with a warning. The NYSERDA FlexTech Program shows up in this tier at "up to $1,000,000" with a competitiveness of 1 of 5 and a 5-hour application, which reads like the best deal on the page. It is not, for a small business: our catalog's realistic-payout note puts typical small-business FlexTech cost-share at $2,000–$25,000, because the award scales to the cost of an energy study and a small building's study is small. One caveat we will not paper over — NYSERDA's own FlexTech page is script-rendered and could not be machine-read on August 24, 2026, so the cost-share percentage and the $1,000,000 ceiling shown in the table are our stored values rather than values re-read at source today. Call NYSERDA before you plan around either number. Programmes like it are why this page prints an advertised ceiling and a competition score side by side instead of ranking on the headline number.

What changed in this slice

A maintained page should show its repairs. These are the dated corrections and status changes that touched $50,000-plus programs in the GrantCompass catalog in the weeks before this page was built. Each monthly recomputation appends to this list rather than replacing it.

Every row above carries locked intel

Knowing a $50,000 programme exists is the easy half. Every row in the table also carries a Win Layer — our analysis of who actually wins it and why applications fail. Across these 68 programs, 62 carry at least five of the seven Win Layer fields and 8 carry all seven.

At this tier the "when cash actually lands" field is the one that changes decisions, because 13 of these 68 programmes pay only after you have already spent. Pro unlocks all seven fields on all 665 programs, plus deadline alerts. $49/mo · $249/yr.

See what Pro unlocks →

Work the whole database, sorted by size

This page is one slice of one date. The database holds all 665 US programs with what is true about each: type, level, status, advertised ceiling, realistic payout and estimated effort. The link below opens it filtered to open programmes and sorted by advertised maximum, largest first — so loans and tax credits appear alongside grants and you can see the whole capital picture at this size. Star what fits, and we watch the deadlines for you. Free.

Open the biggest-first view →

Questions people ask about grants of this size

“What is the largest small business grant I can actually get?”

The largest advertised numbers in this slice belong to federal research vehicles and state deal-making instruments, and neither is what most people mean by the question. Of the 68 open programmes at $50,000 or more, the ones an ordinary operating business files itself and can realistically win top out in the low hundreds of thousands: the Chicago Neighborhood Opportunity Fund and Chicago INVEST South/West at up to $250,000, the Alabama Innovation Grant at up to $250,000 for a company holding a federal SBIR award, the City of Dallas Small Business Assistance Program at up to $400,000. Above that, the numbers describe projects with municipal or institutional partners. For the ranked view of the biggest programmes across the whole catalog rather than only the open ones, see the biggest small business grants.

“Are there $50,000 grants with no deadline?”

Yes, and they are the majority. Forty-five of the 68 open programmes at this tier accept applications on a rolling basis, including the Connecticut Manufacturing Innovation Fund Voucher Program, the Wyoming SBIR/STTR Match Grant, the Nebraska Innovation Fund Prototype Grant at up to $150,000, the Illinois Innovation Voucher Program at up to $75,000 and the Maine Technology Institute Business Innovation Seed Grant at $5,000 to $50,000. Rolling does not mean permanent: most of these are funded from an annual appropriation and stop when it is spent, which is a different and quieter kind of deadline. The full year-round list across all award sizes is at no-deadline small business grants.

“Is a $50,000 grant harder to get than a $5,000 one?”

It is harder to apply for and only slightly harder to win. This dataset puts mean competitiveness at 3.28 of 5 for open grants of $50,000 and above against 2.90 of 5 for open grants under $25,000 — a real difference, but a small one next to the six-fold difference in application hours. The reason is that the two tiers draw different pools. A $5,000 microgrant is open to every business in the country and attracts thousands of two-hour applications; a $75,000 state innovation voucher is open only to companies in one state, in named industries, with a defined project and often a matching contribution, and most of the country self-selects out before writing anything. Narrow eligibility is what keeps large-grant competition lower than intuition predicts.

“How long does a $50,000+ grant take to pay out?”

Longer than the application, and at this tier the payment structure is the part to check first. Thirteen of the 68 open programmes are explicitly reimbursements, which means the business spends first and is repaid on documentation. Match programmes require the company's contribution to be committed before or alongside the award. Federal research awards run on a drawdown schedule against an approved budget. State job-creation and payroll-rebate instruments — Oklahoma's Quality Jobs programmes, Arkansas's CREATE Rebate — pay quarterly over as long as ten years, after the jobs exist. This page does not publish per-programme payment timing; the point here is that "up to $500,000" and "$500,000 in your account" are separated by a structure worth reading before you write.

“What counts as open on this page?”

Open means the programme's status is active in the GrantCompass catalog and it has no published deadline that has already passed — so a rolling intake and a future dated deadline both count. It does not mean money remains, and it does not override what the funder says. Nine of the 68 arrived carrying something that qualified the word, and each was read at the funder's page before this page was published. Six resolved as genuinely open — the Colorado Advanced Industries grants close on August 27, the DOE ITAC Implementation Grant is active again, and the four National Institutes of Health rows are on a live September 5 receipt date. Three still stand: National Science Foundation Project Pitch submissions were paused in April 2026, its STTR Phase I pitches with them, and the Alabama Innovation Grant runs periodic rounds rather than rolling intake. One new flag was raised on August 24 against the Arizona Advanced Manufacturing Facilities Grant, which is not on the Arizona Commerce Authority's current programme index. Those four carry a Check status tag. A list that hides those to keep a count round is telling you about doors, not about money.